Gopal Krishna Ramadas Dhondalay PhD

Project | 26

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Investigation of Neutrophil biomechanical features in idiopathic pulmonary fibrosis

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Summary

  

The idiopathic pulmonary fibrosis (IPF) severity is measured using the clinical features such as Forced vital capacity (FVC): A percentage that measures how much air a patient can exhale after a maximal inhalation. A classification system for IPF severity is based on the 95% confidence interval of FVC. Diffusing capacity of the lung for carbon monoxide (DLCO): A lung function parameter that is used to measure IPF severity. High-resolution CT scan (HRCT): A scan that shows how much scarring is in the lungs. Six-minute walk test: A test that measures a patient's exercise capacity. CALIPER: A quantitative tool that can improve staging systems for IPF. The biomechanical features such as cell porosity, deformability, elasticity and volume. A focused investigation across smoking history between IPF patients and age-matched controls are planned in this project.