Gopal Krishna R Dhondalay PhD
Data Scientist / Bioinformatician / Computational Biologist / Human Geneticist
Scientific Publications [Google Scholar profile]
2022
Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19.
Feyaerts D, Hedou J, Gillard J, Chen H, Tsai ES, Peterson LS, Ando K, Manohar M, Do E, Dhondalay GKR, Fitzpatrick J, Artandi M, Chang I, Snow TT, Chinthrajah RS, Warren CM, Wittman R, Meyerowitz JG, Ganio EA, Stelzer IA, Han X, Verdonk F, Gaudilliere DK, Mukherjee N, Tsai AS, Rumer KK, Jiang SJ, Valdes-Ferrer SI, Kelly JD, Furman D, Aghaeepour N, Angst MS, Boyd SD, Pinsky BA, Nolan GP, Nadeau KC, Gaudilliere B, McIlwain DR.
Cell Reports Medicine 2022 July, 3(7):100680
doi:https://doi.org/10.1016/j.xcrm.2022.100680
(https://www.sciencedirect.com/science/article/pii/S2666379122002166)
Asthma phenotypes, associated comorbidities, and long-term symptoms in COVID-19.
Eggert LE, He Z, Collins W, Lee AS, Dhondalay G, Jiang SY, Fitzpatrick J, Snow TT, Pinsky BA, Artandi M, Barman L, Puri R, Wittman R, Ahuja N, Blomkalns A, O'Hara R, Cao S, Desai M, Sindher SB, Nadeau K, Chinthrajah RS.
Allergy.2022 Jan;77(1):173-185.
doi: 10.1111/all.14972. Epub 2021 Jun 19.
(https://pubmed.ncbi.nlm.nih.gov/34080210/)
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM,Palanski BA, Mallajosyula VVA, Bracey NA, Dhondalay GKR, Bhamidipati K, Pai J, Kipp LB, Dunn JE, Hauser SL, Oksenberg JR, Satpathy AT, Robinson WH, Dekker CL, Steinmetz LM, Khosla C, Utz PJ, Sollid LM, Chien YH, Heath JR, Fernandez-Becker NQ, Nadeau KC, Saligrama N, Davis MM.
Science. 2022 Apr 15;376(6590):eabi9591.
doi: 10.1126/science.abi9591. Epub 2022 Apr 15.
(https://pubmed.ncbi.nlm.nih.gov/35258337/)
Gastrointestinal γδ T cells reveal differentially expressed transcripts and enriched pathways during peanut oral immunotherapy.
Zhang W, Dhondalay GK, Liu TA, Kaushik A, Hoh R, Kwok S, Kambham N, Fernandez-Becker NQ, Andorf S, Desai M, Galli SJ, Boyd SD, Nadeau KC, Manohar M, DeKruyff RH, Chinthrajah RS.
Allergy. 2022 May;77(5):1606-1610.
doi: 10.1111/all.15250. Epub 2022 Feb 18.
(https://pubmed.ncbi.nlm.nih.gov/35143054/)
2021
The allergic asthma phenotype, associated comorbidities, and long-term symptoms in COVID-19.
Lee AS, He Z, Eggert LE, Collins W, Dhondalay G, Jiang SY, Fitzpatrick J, Snow TT, Desai M, Sindher SB, Nadeau KC.
In ALLERGY 2021 Nov 1 (Vol. 76, pp. 199-200). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
A052 Exploratory studies on human GI-resident gamma delta T Cells before and after peanut oral immunotherapy.
Liu T, Zhang W, Dhondalay G, Kambham N, Manohar M, Chinthrajah S, Nadeau K.
ABSTRACT ONLY| VOLUME 127, ISSUE 5, SUPPLEMENT , S9, NOVEMBER 01, 2021
doi:https://doi.org/10.1016/j.anai.2021.08.036
(https://www.annallergy.org/article/S1081-1206(21)00611-6/fulltext)
Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy.
Sharif H, Acharya S, Dhondalay GKR, Varricchi G, Krasner-Macleod S, Laisuan W, Switzer A, Lenormand M, Kashe E, Parkin RV, Yi Y, Koc M, Fedina O, Vilà-Nadal G, Marone G, Eifan A, Scadding GW, Fear DJ, Nadeau KC, Durham SR, Shamji MH.
J Allergy Clin Immunol. 2021 Feb;147(2):663-676. doi: 10.1016/j.jaci.2020.10.035. Epub 2020 Nov 6.
(https://pubmed.ncbi.nlm.nih.gov/33160969/)
Asthma as a predictor of more severe outcomes in COVID-19 infection
Eggert L, Cao S, He Z, Dhondalay GK, Jiang S, Collins W, Sindher S, Nadeau K, Chinthrajah C
ABSTRACT ONLY| VOLUME 147, ISSUE 2, SUPPLEMENT , AB44, FEBRUARY 01, 2021
DOI:https://doi.org/10.1016/j.jaci.2020.12.191
(https://www.jacionline.org/article/S0091-6749(20)31954-0/fulltext)
Transcriptomics Of Gastrointestinal Biopsies During Oral Immunotherapy Reveals Changes In IgA Pathway
Dhondalay GK, Zhang W, Hoh R, Kambham N, Boyd S, Andorf S, Manohar M, Chinthrajah S, Nadeau
ABSTRACT ONLY| VOLUME 147, ISSUE 2, SUPPLEMENT, AB166, FEBRUARY 01, 2021
doi:https://doi.org/10.1016/j.jaci.2020.12.590
(https://www.jacionline.org/article/S0091-6749(20)32353-8/fulltext)
2020
RNA-Seq of Gastrointestinal Biopsies During Oral Immunotherapy Reveals Changes in IgA Pathway
Zhang W, Dhondalay G, Hoh R, Tupa D, Bunning B, Fernandez-Becker N, Kambham N, Boyd S, Galli S, Andorf S, Manohar M, Chinthrajah S, Nadeau K
ABSTRACT ONLY| VOLUME 145, ISSUE 2, SUPPLEMENT , AB132, FEBRUARY 01, 2020
doi:https://doi.org/10.1016/j.jaci.2019.12.524
(https://www.jacionline.org/article/S0091-6749(19)32226-2/fulltext)
Transcriptional changes in peanut-specific CD4+ T cells over the course of oral immunotherapy.
Wang W, Lyu SC, Ji X, Gupta S, Manohar M, Dhondalay GKR, Chinthrajah S, Andorf S, Boyd SD, Tibshirani R, Galli SJ, Nadeau KC, Maecker HT.
Clin Immunol. 2020 Aug 9;219:108568.
(https://pubmed.ncbi.nlm.nih.gov/32783912/)
Transcriptomic and methylomic features in asthmatic and nonasthmatic twins.
Dhondalay GKR, Bunning B, Bauer RN, Barnathan ES, Maniscalco C, Baribaud F, Nadeau KC, Andorf S.
Allergy. 2020 Apr;75(4):989-992.
(https://pubmed.ncbi.nlm.nih.gov/31758558/)
Global metabolic profiling to model biological processes of aging in twins.
Bunning BJ, Contrepois K, Lee-McMullen B, Dhondalay GKR, Zhang W, Tupa D, Raeber O, Desai M, Nadeau KC, Snyder MP, Andorf S.
Aging Cell. 2020 Jan;19(1):e13073.
(https://pubmed.ncbi.nlm.nih.gov/31746094/)
2019
Altered chromatin landscape in T follicular cells in seasonal allergic rhinitis and following allergen‐specific immunotherapy.
Sharif H, Acharya S, Dhondalay GK, Krasner‐Macleod S, Parkin R, Scadding G, Durham S, Nadeau KC, Shamji M.
In ALLERGY 2019 Aug 1 (Vol. 74, pp. 64-65). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
2018
Food allergy and omics.
Dhondalay GK, Rael E, Acharya S, Zhang W, Sampath V, Galli SJ, Tibshirani R, Boyd SD, Maecker H, Nadeau KC, Andorf S.
J Allergy Clin Immunol. 2018 Jan;141(1):20-29. doi: 10.1016/j.jaci.2017.11.007.
(https://pubmed.ncbi.nlm.nih.gov/29307411/)
2017
HER2/neu Testing In 432 Consecutive Breast Cancer Cases using FISH and IHC - A Comparative Study.
Eswarachary V, Mohammed IG, Jayanna PK, Patilokaly GV, Nargund AR, Dhondalay GK, Prabhudesai S, Sahoo R.
J Clin Diagn Res. 2017 Apr;11(4):EC01-EC05.
(https://pubmed.ncbi.nlm.nih.gov/28571140/)
2014
Relationship between preparation of cells for therapy and cell quality using artificial neural network analysis.
Dhondalay GK, Lawrence K, Ward S, Ball G, Hoare M.
Artif Intell Med. 2014 Oct;62(2):119-27.
(https://pubmed.ncbi.nlm.nih.gov/25239560/)
Artificial Neural Network Inference (ANNI): A Study on Gene-Gene Interaction for Biomarkers in Childhood Sarcomas.
Tong DL, Boocock DJ, Dhondalay GK, Lemetre C, Ball GR.
PLoS ONE 9(7): e102483.
(https://pubmed.ncbi.nlm.nih.gov/25025207/)
DACH1: its role as a classifier and prognostic marker in luminal breast cancer.
Dhondalay GK, Powe DG, Lemetre C, Allen T, Habashy HO, Ellis IO, Rees R, Ball GR.
PLoS One 2014 Jan 2;9(1):e84428.
(https://pubmed.ncbi.nlm.nih.gov/24392136/) (as first co-author).
2013
Biomarker identification in breast cancer: Beta-adrenergic receptor signaling and pathways to therapeutic response.
Kafetzopoulou LE, Boocock DJ, Dhondalay GK, Powe DG, Ball GR.
Computational and Structural Biotechnology Journal. 03/2013; 6(7) e201303003.
(https://pubmed.ncbi.nlm.nih.gov/24688711/)
2012
Modelling estrogen receptor pathways in breast cancer using an Artificial Neural Networks based inference approach.
Dhondalay GK, Lemetre C, Ball GR.
Proceedings of the IEEE-EMBS International Conference on Biomedical and Health Informatics. Hong Kong, Shenzhen, 5-7 January 2012.
(https://ieeexplore.ieee.org/document/6211745)
2011
Estrogen receptor status prediction for breast cancer using artificial neural network.
Dhondalay GK, Tong DL, Ball GR.
Proceedings of the 2011 International Conference on Machine Learning and Cybernetics, Guilin, 10-13 July, 2011.
(https://ieeexplore.ieee.org/document/6016771)
Her-2/neu overexpression due to polysomy 17 in breast cancer: Molecular testing to guide therapeutic options.
Sahoo R, Babu VC, Harini VV, Patil GV, Dhondalay GK, Kulkarni J, Nargund AR, Rao S, Venkataswamy E, Ajaikumar BS, Mohan Rao R.
Onkologie 2011;34:356-360.
(https://pubmed.ncbi.nlm.nih.gov/21734421/)
2009
Relationship between molecular markers and treatment response in a retrospective cohort of Indian patients with primary Ca larynx.
Sahoo R, Chittibabu V, Patil G, Rao S, Thakur S, Dhondalay G, Kulkarni AJ, Banerjee A, Ajaikumar BS, Korlimarla A, Nargund A, Niti RN, Gopinath KS, Prabhudesai S, Raghavendra RM.
Oral Oncology 2009 Dec;45(12):e216-21.
(https://pubmed.ncbi.nlm.nih.gov/19729336/)